Dysregulation of nuclear receptor COUP-TFII impairs skeletal muscle development

Abstract Chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) has been shown to inhibit myogenesis and skeletal muscle metabolism in vitro. However, its precise role and in vivo function in muscle development has yet to be clearly defined. COUP-TFII protein expression level is hig...

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Bibliographic Details
Main Authors: Hui-Ju Lee, Chung-Yang Kao, Shih-Chieh Lin, Mafei Xu, Xin Xie, Sophia Y. Tsai, Ming-Jer Tsai
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03475-5