Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domain

Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domain

<p>Abstract</p> <p>Background</p> <p>The polycomb group (PcG) protein BMI1 is an important regulator of development. Additionally, aberrant expression of BMI1 has been linked to cancer stem cell phenotype and oncogenesis. In particular, its overexpression has been found...

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Bibliographic Details
Main Authors: Bommi Prashant V, Dimri Manjari, Sahasrabuddhe Anagh A, Yadav Ajay K, Sainger Rachana, Dimri Goberdhan P
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/158

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