Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domain
<p>Abstract</p> <p>Background</p> <p>The polycomb group (PcG) protein BMI1 is an important regulator of development. Additionally, aberrant expression of BMI1 has been linked to cancer stem cell phenotype and oncogenesis. In particular, its overexpression has been found...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-06-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/9/1/158 |