Assessment of the Role of Renal Organic Anion Transporters in Drug-Induced Nephrotoxicity

In the present review we have attempted to assess the involvement of the organic anion transporters OAT1, OAT2, OAT3, and OAT4, belonging to the SLC22 family of polyspecific carriers, in drug-induced renal damage in humans. We have focused on drugs with widely recognized nephrotoxic potential, which...

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Bibliographic Details
Main Authors: Natascha A. Wolff, Yohannes Hagos
Format: Article
Language:English
Published: MDPI AG 2010-08-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/2/8/2055/