A Dual Role of Heme Oxygenase-1 in Angiotensin II-Induced Abdominal Aortic Aneurysm in the Normolipidemic Mice

Abdominal aortic aneurysm (AAA) bears a high risk of rupture and sudden death of the patient. The pathogenic mechanisms of AAA remain elusive, and surgical intervention represents the only treatment option. Heme oxygenase-1 (HO-1), a heme degrading enzyme, is induced in AAA, both in mice and humans....

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Bibliographic Details
Main Authors: Aleksandra Kopacz, Damian Klóska, Ewa Werner, Karolina Hajduk, Anna Grochot-Przęczek, Alicja Józkowicz, Aleksandra Piechota-Polańczyk
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
AAA
Online Access:https://www.mdpi.com/2073-4409/10/1/163