HIVIntact: a python-based tool for HIV-1 genome intactness inference

Abstract The characterisation of the HIV-1 reservoir, which consists of replication-competent integrated proviruses that persist on antiretroviral therapy (ART), is made difficult by the rarity of intact proviruses relative to those that are defective. While the only conclusive test for the replicat...

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Bibliographic Details
Main Authors: Imogen A. Wright, Michael J. Bale, Wei Shao, Wei-Shau Hu, John M. Coffin, Gert U. Van Zyl, Mary F. Kearney
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Retrovirology
Online Access:https://doi.org/10.1186/s12977-021-00561-5