Organization and evolution of primate centromeric DNA from whole-genome shotgun sequence data.

The major DNA constituent of primate centromeres is alpha satellite DNA. As much as 2%-5% of sequence generated as part of primate genome sequencing projects consists of this material, which is fragmented or not assembled as part of published genome sequences due to its highly repetitive nature. Her...

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Bibliographic Details
Main Authors: Can Alkan, Mario Ventura, Nicoletta Archidiacono, Mariano Rocchi, S Cenk Sahinalp, Evan E Eichler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1994983?pdf=render