Cholinergic stimulation with pyridostigmine modulates a heart-spleen axis after acute myocardial infarction in spontaneous hypertensive rats

Cholinergic stimulation with pyridostigmine modulates a heart-spleen axis after acute myocardial infarction in spontaneous hypertensive rats

Abstract The mechanisms regulating immune cells recruitment into the heart during healing after an acute myocardial infarction (AMI) have major clinical implications. We investigated whether cholinergic stimulation with pyridostigmine, a cholinesterase inhibitor, modulates heart and spleen immune re...

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Bibliographic Details
Main Authors: Robson Luiz Bandoni, Pamela Nithzi Bricher Choque, Humberto Dellê, Tercio Lemos de Moraes, Maria Helena Mattos Porter, Bruno Durante da Silva, Gizele Alves Neves, Maria-Claudia Irigoyen, Kátia De Angelis, Valentin A. Pavlov, Luis Ulloa, Fernanda Marciano Consolim-Colombo
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89104-8

Internet

https://doi.org/10.1038/s41598-021-89104-8

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