Metoprolol alleviates arginine vasopressin-induced cardiomyocyte hypertrophy by upregulating the AKT1–SERCA2 cascade in H9C2 cells
Abstract Background Arginine vasopressin (AVP) is elevated in patients with heart failure, and the increase in the AVP concentration in plasma is positively correlated with disease severity and mortality. Metoprolol (Met) is a beta blocker that is widely used in the clinic to treat pathological card...
Main Authors: | Jieqiong Zhao, Yonghong Lei, Yanping Yang, Haibo Gao, Zhongchao Gai, Xue Li |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
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Series: | Cell & Bioscience |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13578-020-00434-y |
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