Autophagy Drives Galectin-1 Secretion From Tumor-Associated Macrophages Facilitating Hepatocellular Carcinoma Progression

Autophagy Drives Galectin-1 Secretion From Tumor-Associated Macrophages Facilitating Hepatocellular Carcinoma Progression

Galectin-1 (Gal-1) is a secretory lectin with pro-tumor activities and is associated strongly with hepatocellular carcinoma (HCC) development. Although Gal-1 is a well-known soluble pro-tumor factor in the tumor microenvironment (TME), the secretion mode of Gal-1 is not clearly defined. On the other...

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Bibliographic Details
Main Authors: Goutham Venkata Naga Davuluri, Chien-Chin Chen, Yen-Cheng Chiu, Hung-Wen Tsai, Hung-Chih Chiu, Yuh-Ling Chen, Pei-Jane Tsai, Wan-Ting Kuo, Nina Tsao, Yee-Shin Lin, Chih-Peng Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
galectin-1
hepatocellular carcinoma
secretory autophagy
tumor-associated macrophages
toll-like receptor 2
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.741820/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.741820/full

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