Dexamethasone Suppresses Histamine Synthesis by Repressing both Transcription and Activity of HDC in Allergic Rats

Background: Histamine synthesized by histidine decarboxylase (HDC) from L-histidine is a major chemical mediator in the development of nasal allergy which is characterized by nasal hypersensitivity. However the regulatory mechanism of histamine synthesis by HDC remains to be elucidated. The objectiv...

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Bibliographic Details
Main Authors: Yoshiaki Kitamura, Asish K Das, Yuki Murata, Kazutaka Maeyama, Shrabanti Dev, Yousuke Wakayama, Bukasa Kalubi, Noriaki Takeda, Hiroyuki Fukui
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Allergology International
Subjects:
HDC
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015309771