The role of Sphingomyelin synthase 2 (SMS2) in platelet activation and its clinical significance

Abstract Background Sphingomyelin (SM) is an essential component of biological lipid rafts, and it plays an indispensable role in maintaining plasma membrane stability and in mediating signal transduction. The ultimate biosynthesis of SM is catalyzed by two sphingomyelin synthases (SMSs) namely SMS1...

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Bibliographic Details
Main Authors: Yifan Guo, Lin Chang, Ge Zhang, Zhanyan Gao, Hao Lin, Yuting Zhang, Liang Hu, She Chen, Bing Fan, Si Zhang, Ruyi Xue
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Thrombosis Journal
Subjects:
Online Access:https://doi.org/10.1186/s12959-021-00282-x