Genetic dissection of the mitochondrial lipoylation pathway in yeast

Abstract Background Lipoylation of 2-ketoacid dehydrogenases is essential for mitochondrial function in eukaryotes. While the basic principles of the lipoylation processes have been worked out, we still lack a thorough understanding of the details of this important post-translational modification pa...

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Bibliographic Details
Main Authors: Laura P. Pietikäinen, M. Tanvir Rahman, J. Kalervo Hiltunen, Carol L. Dieckmann, Alexander J. Kastaniotis
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-021-00951-3