Enhanced sensitivity to low dose irradiation of ApoE-/- mice mediated by early pro-inflammatory profile and delayed activation of the TGFβ1 cascade involved in fibrogenesis.

Enhanced sensitivity to low dose irradiation of ApoE-/- mice mediated by early pro-inflammatory profile and delayed activation of the TGFβ1 cascade involved in fibrogenesis.

AIM: Investigating long-term cardiac effects of low doses of ionizing radiation is highly relevant in the context of interventional cardiology and radiotherapy. Epidemiological data report that low doses of irradiation to the heart can result in significant increase in the cardiovascular mortality b...

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Bibliographic Details
Main Authors: Virginie Monceau, Lydia Meziani, Carine Strup-Perrot, Eric Morel, Magret Schmidt, Julia Haagen, Brigitte Escoubet, Wolfgang Dörr, Marie-Catherine Vozenin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3579799?pdf=render

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http://europepmc.org/articles/PMC3579799?pdf=render

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