Immature morphological properties in subcellular-scale structures in the dentate gyrus of Schnurri-2 knockout mice: a model for schizophrenia and intellectual disability

Immature morphological properties in subcellular-scale structures in the dentate gyrus of Schnurri-2 knockout mice: a model for schizophrenia and intellectual disability

Abstract Accumulating evidence suggests that subcellular-scale structures such as dendritic spine and mitochondria may be involved in the pathogenesis/pathophysiology of schizophrenia and intellectual disability. Previously, we proposed mice lacking Schnurri-2 (Shn2; also called major histocompatibi...

Full description

Bibliographic Details
Main Authors: Akito Nakao, Naoyuki Miyazaki, Koji Ohira, Hideo Hagihara, Tsuyoshi Takagi, Nobuteru Usuda, Shunsuke Ishii, Kazuyoshi Murata, Tsuyoshi Miyakawa
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Molecular Brain
Subjects:
Mouse model
Schizophrenia
Intellectual disability
3D electron microscopy
Online Access:http://link.springer.com/article/10.1186/s13041-017-0339-2

Internet

http://link.springer.com/article/10.1186/s13041-017-0339-2

Similar Items