High risk of patient self-inflicted lung injury in COVID-19 with frequently encountered spontaneous breathing patterns: a computational modelling study

Abstract Background There is on-going controversy regarding the potential for increased respiratory effort to generate patient self-inflicted lung injury (P-SILI) in spontaneously breathing patients with COVID-19 acute hypoxaemic respiratory failure. However, direct clinical evidence linking increas...

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Bibliographic Details
Main Authors: Liam Weaver, Anup Das, Sina Saffaran, Nadir Yehya, Timothy E. Scott, Marc Chikhani, John G. Laffey, Jonathan G. Hardman, Luigi Camporota, Declan G. Bates
Format: Article
Language:English
Published: SpringerOpen 2021-07-01
Series:Annals of Intensive Care
Subjects:
Online Access:https://doi.org/10.1186/s13613-021-00904-7