SST gene hypermethylation acts as a pan‐cancer marker for pancreatic ductal adenocarcinoma and multiple other tumors: toward its use for blood‐based diagnosis

SST gene hypermethylation acts as a pan‐cancer marker for pancreatic ductal adenocarcinoma and multiple other tumors: toward its use for blood‐based diagnosis

Aberrant DNA methylation is often involved in carcinogenesis. Our initial goal was to identify DNA methylation biomarkers associated with pancreatic cancer. A genomewide methylation study was performed on DNA from pancreatic ductal adenocarcinoma (PDAC) and endocrine pancreas tumors. Validation of D...

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Bibliographic Details
Main Authors: Mehdi Manoochehri, Yenan Wu, Nathalia A. Giese, Oliver Strobel, Stefanie Kutschmann, Florian Haller, Jörg D. Hoheisel, Evgeny A. Moskalev, Thilo Hackert, Andrea S. Bauer
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Molecular Oncology
Subjects:
biomarker
DNA methylation
gene expression
liquid biopsy
pancreatic cancer
solid tumors
Online Access:https://doi.org/10.1002/1878-0261.12684

Internet

https://doi.org/10.1002/1878-0261.12684

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