Protectin DX increases survival in a mouse model of sepsis by ameliorating inflammation and modulating macrophage phenotype

Abstract Recently, a serial of studies have demonstrated that lipid mediators derived from Omega-3 fatty acid docosahexaenoic acid have pro-resolving or anti-inflammatory effects in many inflammatory diseases. Here, we sought to evaluate whether Protectin DX (PDX, an isomer of Protecin D1), a newly...

Full description

Bibliographic Details
Main Authors: Haifa Xia, Lin Chen, Hong Liu, Zhipeng Sun, Wen Yang, Yiyi Yang, Shunan Cui, Shengnan Li, Yaxin Wang, Limin Song, Amro Fayez Abdelgawad, You Shang, Shanglong Yao
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00103-0