Hedgehog Promotes Production of Inhibitory Interneurons in Vivo and in Vitro from Pluripotent Stem Cells

Loss or damage of cortical inhibitory interneurons characterizes a number of neurological disorders. There is therefore a great deal of interest in learning how to generate these neurons from a pluripotent stem cell source so they can be used for cell replacement therapies or for in vitro drug testi...

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Bibliographic Details
Main Authors: Nickesha C. Anderson, Christopher Y. Chen, Laura Grabel
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Journal of Developmental Biology
Subjects:
Online Access:http://www.mdpi.com/2221-3759/4/3/26