Bisbenzylisoquinoline Alkaloids of Cissampelos Sympodialis With in Vitro Antiviral Activity Against Zika Virus

Bisbenzylisoquinoline Alkaloids of Cissampelos Sympodialis With in Vitro Antiviral Activity Against Zika Virus

In search of new antiviral compounds against Zika virus we conducted a bioassay-guided fractionation of bisbenzyilisoquinoline alkaloids isolated from Cissampelos sympodialis (Menispermaceae), a medicinal plant species endemic to Brazil. Six subfractions were obtained from a tertiary alkaloidal frac...

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Bibliographic Details
Main Authors: Poliana Gomes da Silva, Aventino H. Fonseca, Malu P. Ribeiro, Taizia D. Silva, Cristiane F. F. Grael, Lindomar J. Pena, Tania M. S. Silva, Eduardo de Jesus Oliveira
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
Cissampelos sympodialis
Zika virus
antiviral activity
warifteine
methylwarifteine
bisbenzylisoquinoline alkaloids
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.743541/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.743541/full

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