Calcium-driven regulation of voltage-sensing domains in BK channels

Calcium-driven regulation of voltage-sensing domains in BK channels

Allosteric interactions between the voltage-sensing domain (VSD), the Ca2+-binding sites, and the pore domain govern the mammalian Ca2+- and voltage-activated K+ (BK) channel opening. However, the functional relevance of the crosstalk between the Ca2+- and voltage-sensing mechanisms on BK channel ga...

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Bibliographic Details
Main Authors: Yenisleidy Lorenzo-Ceballos, Willy Carrasquel-Ursulaez, Karen Castillo, Osvaldo Alvarez, Ramon Latorre
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
gating currents
Ca2+ binding
allosteric coupling
Online Access:https://elifesciences.org/articles/44934

Internet

https://elifesciences.org/articles/44934

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