Phospholipids induce conformational changes of SecA to form membrane-specific domains: AFM structures and implication on protein-conducting channels.

Phospholipids induce conformational changes of SecA to form membrane-specific domains: AFM structures and implication on protein-conducting channels.

SecA, an essential component of the Sec machinery, exists in a soluble and a membrane form in Escherichia coli. Previous studies have shown that the soluble SecA transforms into pore structures when it interacts with liposomes, and integrates into membranes containing SecYEG in two forms: SecAS and...

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Bibliographic Details
Main Authors: Zhipeng You, Meijiang Liao, Hao Zhang, Hsiuchin Yang, Xijian Pan, John E Houghton, Sen-Fang Sui, Phang C Tai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3745498?pdf=render

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http://europepmc.org/articles/PMC3745498?pdf=render

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