Genotoxic effect of non-lethal concentrations of minocycline in human glial cell culture

Genotoxic effect of non-lethal concentrations of minocycline in human glial cell culture

Minocycline has been proposed as a neuroprotective agent with pleiotropic effects on several experimental models of neurodegenerative diseases, including microglial inhibition. However, although most studies have focused on the central actions of minocycline in affecting microglial functions, other...

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Bibliographic Details
Main Authors: Bruna Puty, Iago César da Costa Nogueira, Lygia S. Nogueira, Carolina Pinheiro Vasconcelos, Teka Mayara Corrêa Araújo, Leonardo Oliveira Bittencourt, Railson de Oliveira Ferreira, Edivaldo Herculano C. de Oliveira, Walace Gomes Leal, Rafael Rodrigues Lima
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Cytotoxicity
DNA damage
Glia
Minocycline
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220304777

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http://www.sciencedirect.com/science/article/pii/S0753332220304777

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