Mottled mice and non-mammalian models of Menkes disease

Mottled mice and non-mammalian models of Menkes disease

Menkes disease is a multi-systemic copper metabolism disorder caused by mutations in the X-linked ATP7A gene and characterised by progressive neurodegeneration and severe connective tissue defects. The ATP7A protein is a Copper (Cu)-transporting ATPase expressed in all tissues and plays a critical r...

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Bibliographic Details
Main Authors: malgorzata elenartowicz, Wojciech eKrzeptowski, Paweł eLipinski, Pawel eGrzmil, Rafał eStarzyński, Olga ePierzchała, Lisbeth Birk eMøller
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Animal Models
ATP7A
Menkes disease
Copper metabolism
Mottled mice
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00072/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00072/full

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