From biomarkers to a clue of biology: a computation-aided perspective of immune gene expression profiles in human type 1 diabetes

From biomarkers to a clue of biology: a computation-aided perspective of immune gene expression profiles in human type 1 diabetes

Dysregulated expression of key immune genes may cause breakdown of immunological tolerance and development of autoimmune disorders such as type 1 diabetes (T1D). General immune insufficiencies have also been implicated as a trigger of autoimmunity, due to their potential impact on immune homeostasis...

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Bibliographic Details
Main Authors: Dongmei eHan, Xiaodong eCai, Ji eWen, Norma eKenyon, Zhibin eChen
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Immunology
Subjects:
Autoimmunity
Diabetes Mellitus
Gene Expression
Humans
human
diabetes
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00320/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00320/full

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