EPR Spectroscopy of a Clinically Active (1:2) Copper(II)-Histidine Complex Used in the Treatment of Menkes Disease: A Fourier Transform Analysis of a Fluid CW-EPR Spectrum

Redox active transition metal ions (e.g., iron and copper) have been implicated in the etiology of many oxidative stress-related diseases including also neurodegenerative disorders. Unbound copper can catalyze formation of reactive oxygen species (hydroxyl radicals) via Fenton reaction/Haber–Weiss c...

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Bibliographic Details
Main Authors: Lukas Gala, Michael Lawson, Klaudia Jomova, Lubomir Zelenicky, Andrea Congradyova, Milan Mazur, Marian Valko
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/1/980