Downregulation of 5-hydroxymethylcytosine is associated with the progression of cervical intraepithelial neoplasia.

Around the world, cervical cancer is one of the most common neoplastic diseases among women, and the prognosis of patients in an advanced stage remains poor. To reduce the mortality rate of cervical cancer, early diagnosis and treatment are essential. DNA methylation is an important aspect of gene r...

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Bibliographic Details
Main Authors: Masaya Kato, Ichiro Onoyama, Minoru Kawakami, Sachiko Yoshida, Keiko Kawamura, Keisuke Kodama, Emiko Hori, Lin Cui, Yumiko Matsumura, Hiroshi Yagi, Kazuo Asanoma, Hideaki Yahata, Atsuo Itakura, Satoru Takeda, Kiyoko Kato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0241482