Caudatin Isolated from <i>Cynanchum auriculatum</i> Inhibits Breast Cancer Stem Cell Formation via a GR/YAP Signaling

In the complex tumor microenvironment, cancer stem cells (CSCs), a rare population of cells, are responsible for malignant tumor initiation, metastasis, drug resistance and recurrence. Controlling breast CSCs (BCSCs) using natural compounds is a novel potential therapeutic strategy for clinical canc...

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Bibliographic Details
Main Authors: Xing Zhen, Hack Sun Choi, Ji-Hyang Kim, Su-Lim Kim, Ren Liu, Yu-Chan Ko, Bong-Sik Yun, Dong-Sun Lee
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Biomolecules
Subjects:
YAP
Online Access:https://www.mdpi.com/2218-273X/10/6/925