<i>Naja atra</i> Cardiotoxin 1 Induces the FasL/Fas Death Pathway in Human Leukemia Cells

This study aimed to investigate the mechanistic pathway of <i>Naja atra</i> (Taiwan cobra) cardiotoxin 1 (CTX1)–induced death of leukemia cell lines U937 and HL-60. CTX1 increased cytoplasmic Ca<sup>2+</sup> and reactive oxygen species (ROS) production, leading to the death o...

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Bibliographic Details
Main Authors: Jing-Ting Chiou, Liang-Jun Wang, Yuan-Chin Lee, Long-Sen Chang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
Fas
Online Access:https://www.mdpi.com/2073-4409/10/8/2073