A protective role for ELR+ chemokines during acute viral encephalomyelitis.

The functional role of ELR-positive CXC chemokines in host defense during acute viral-induced encephalomyelitis was determined. Inoculation of the neurotropic JHM strain of mouse hepatitis virus (JHMV) into the central nervous system (CNS) of mice resulted in the rapid mobilization of PMNs expressin...

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Bibliographic Details
Main Authors: Martin P Hosking, Liping Liu, Richard M Ransohoff, Thomas E Lane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2766051?pdf=render