Genome organization is a major component of gene expression control in response to stress and during the cell division cycle in trypanosomes

The trypanosome genome is characterized by RNA polymerase II-driven polycistronic transcription of protein-coding genes. Ten to hundreds of genes are co-transcribed from a single promoter; thus, selective regulation of individual genes via initiation is impossible. However, selective responses to ex...

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Bibliographic Details
Main Authors: S. Kelly, S. Kramer, A. Schwede, P. K. Maini, K. Gull, M. Carrington
Format: Article
Language:English
Published: The Royal Society 2012-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120033