Genome organization is a major component of gene expression control in response to stress and during the cell division cycle in trypanosomes
The trypanosome genome is characterized by RNA polymerase II-driven polycistronic transcription of protein-coding genes. Ten to hundreds of genes are co-transcribed from a single promoter; thus, selective regulation of individual genes via initiation is impossible. However, selective responses to ex...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2012-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120033 |