Chronic intermittent hypoxia increases encoding pigment epithelium-derived factor gene expression, although not that of the protein itself, in the temporal cortex of rats,

Objective: Obstructive sleep apnea syndrome is mainly characterized by intermittent hypoxia (IH) during sleep, being associated with several complications. Exposure to IH is the most widely used animal model of sleep apnea, short-term IH exposure resulting in cognitive and neuronal impairment. Pigme...

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Bibliographic Details
Main Authors: Guilherme Silva Julian, Renato Watanabe de Oliveira, Vanessa Manchim Favaro, Maria Gabriela Menezes de Oliveira, Juliana Cini Perry, Sergio Tufik, Jair Ribeiro Chagas
Format: Article
Language:English
Published: Sociedade Brasileira de Pneumologia e Tisiologia 2015-02-01
Series:Jornal Brasileiro de Pneumologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132015000100039&lng=en&tlng=en