Linking pre-diabetes with benign prostate hyperplasia. IGFBP-3: a conductor of benign prostate hyperplasia development orchestra?

Benign prostatic hyperplasia (BPH) represents a pattern of non-malignant growth of prostatic fibromuscular stroma. Metabolic disturbances such us pre-diabetes and metabolic syndrome may have a role in BPH pathophysiology. A potential explanation for the above relationship involves the insulin-like g...

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Main Authors: Ioannis Protopsaltis, Achilles Ploumidis, Theodoros N Sergentanis, Padelis Constantoulakis, Kostantinos Tzirogiannis, Chrysoula Kyprianidou, Athanasia K Papazafiropoulou, Andreas Melidonis, Dimitrios Delakas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3868595?pdf=render