Feedback Regulation of Cathepsin C by the Propeptide Dipeptides of Granzymes A and B
Granzymes A and B are activated by proteolytic removal of their N-terminal dipeptides by cathepsin C (dipeptidyl-peptidase I). However, the possible physiological role of the cleaved dipeptides Glu-Lys and Gly-Glu is not yet understood. In this study, adding either of the two dipeptides to NK-92 cel...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Slovenian Chemical Society
2019-06-01
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Series: | Acta Chimica Slovenica |
Subjects: | |
Online Access: | https://journals.matheo.si/index.php/ACSi/article/view/5192 |