Circadian control of mouse heart rate and blood pressure by the suprachiasmatic nuclei: behavioral effects are more significant than direct outputs.

Diurnal variations in the incidence of events such as heart attack and stroke suggest a role for circadian rhythms in the etiology of cardiovascular disease. The aim of this study was to assess the influence of the suprachiasmatic nucleus (SCN) circadian clock on cardiovascular function.Heart rate (...

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Bibliographic Details
Main Authors: W John Sheward, Erik Naylor, Seymour Knowles-Barley, J Douglas Armstrong, Gillian A Brooker, Jonathan R Seckl, Fred W Turek, Megan C Holmes, Phyllis C Zee, Anthony J Harmar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2842429?pdf=render