A DNA methylation-based liquid biopsy for triple-negative breast cancer

Abstract Here, we present a next-generation sequencing (NGS) methylation-based blood test called methylation DETEction of Circulating Tumour DNA (mDETECT) designed for the optimal detection and monitoring of metastatic triple-negative breast cancer (TNBC). Based on a highly multiplexed targeted sequ...

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Bibliographic Details
Main Authors: Katrina Cristall, Francois-Clement Bidard, Jean-Yves Pierga, Michael J. Rauh, Tatiana Popova, Clara Sebbag, Olivier Lantz, Marc-Henri Stern, Christopher R. Mueller
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-021-00198-9