Artesunate Inhibits Growth of Sunitinib-Resistant Renal Cell Carcinoma Cells through Cell Cycle Arrest and Induction of Ferroptosis

Although innovative therapeutic concepts have led to better treatment of advanced renal cell carcinoma (RCC), efficacy is still limited due to the tumor developing resistance to applied drugs. Artesunate (ART) has demonstrated anti-tumor effects in different tumor entities. This study was designed t...

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Bibliographic Details
Main Authors: Sascha D. Markowitsch, Patricia Schupp, Julia Lauckner, Olesya Vakhrusheva, Kimberly S. Slade, René Mager, Thomas Efferth, Axel Haferkamp, Eva Juengel
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/11/3150