Activity to Breast Cancer Cell Lines of Different Malignancy and Predicted Interaction with Protein Kinase C Isoforms of Royleanones

Activity to Breast Cancer Cell Lines of Different Malignancy and Predicted Interaction with Protein Kinase C Isoforms of Royleanones

Plants have been used for centuries to treat several illnesses. The <i>Plectranthus</i> genus has a vast variety of species that has allowed the isolation of cytotoxic compounds with notable activities. The abietane diterpenes 6,7-dehydroroyleanone (DeRoy, <b>1</b>), 7α-aceto...

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Bibliographic Details
Main Authors: Vera M. S. Isca, Milan Sencanski, Nenad Filipovic, Daniel J. V. A. Dos Santos, Ana Čipak Gašparović, Lucília Saraíva, Carlos A. M. Afonso, Patrícia Rijo, Alfonso T. García-Sosa
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Plectranthus</i>
royleanones
hemi-synthesis
PKC activity
isozyme-selectivity
molecular interactions
Online Access:https://www.mdpi.com/1422-0067/21/10/3671

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https://www.mdpi.com/1422-0067/21/10/3671

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