Spatial statistical tools for genome-wide mutation cluster detection under a microarray probe sampling system.

Mutation cluster analysis is critical for understanding certain mutational mechanisms relevant to genetic disease, diversity, and evolution. Yet, whole genome sequencing for detection of mutation clusters is prohibitive with high cost for most organisms and population surveys. Single nucleotide poly...

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Bibliographic Details
Main Authors: Bin Luo, Alanna K Edge, Cornelia Tolg, Eva A Turley, C B Dean, Kathleen A Hill, R J Kulperger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6155535?pdf=render