Immunization route dictates cross-priming efficiency and impacts the optimal timing of adjuvant delivery

Immunization route dictates cross-priming efficiency and impacts the optimal timing of adjuvant delivery

Delivery of cell-associated antigen represents an important strategy for vaccination. While many experimental models have been developed in order to define the critical parameters for efficient cross-priming, few have utilized quantitative methods that permit the study of the endogenous repertoire....

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Bibliographic Details
Main Authors: Isabelle eBouvier, Hélène eJusforgues-Saklani, Annick eLim, Fabrice eLemaître, Brigitte eLemercier, Charlotte eAuriau, Marie-Anne eNicola, Sandrine eLeroy, Helen K Law, Antonio eBandeira, James J Moon, Philippe eBousso, Matthew eAlbert
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Immunology
Subjects:
Cross-Priming
Dendritic Cells
adjuvant delivery
polyfunctional T cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00071/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00071/full

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