HIV-1 quasispecies delineation by tag linkage deep sequencing.

HIV-1 quasispecies delineation by tag linkage deep sequencing.

Trade-offs between throughput, read length, and error rates in high-throughput sequencing limit certain applications such as monitoring viral quasispecies. Here, we describe a molecular-based tag linkage method that allows assemblage of short sequence reads into long DNA fragments. It enables haplot...

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Bibliographic Details
Main Authors: Nicholas C Wu, Justin De La Cruz, Laith Q Al-Mawsawi, C Anders Olson, Hangfei Qi, Harding H Luan, Nguyen Nguyen, Yushen Du, Shuai Le, Ting-Ting Wu, Xinmin Li, Martha J Lewis, Otto O Yang, Ren Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4026136?pdf=render

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http://europepmc.org/articles/PMC4026136?pdf=render

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