HIV p24 as scaffold for presenting conformational HIV Env antigens.

Heterologous protein scaffolds engrafted with structurally defined HIV Env epitopes recognized by broadly neutralizing monoclonal antibodies (MAbs) represent a promising strategy to elicit broad neutralizing antibodies. In such regards, a protein scaffold based on the HIV p24 CA protein is a highly...

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Bibliographic Details
Main Authors: Maria Tagliamonte, Daniela Marasco, Alessia Ruggiero, Angelo De Stradis, Maria Lina Tornesello, Maxim Totrov, Franco Maria Buonaguro, Luigi Buonaguro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3422313?pdf=render