Deregulated expression of cytoskeleton related genes in the spinal cord and sciatic nerve of presymptomatic SOD1G93A Amyotrophic Lateral Sclerosis mouse model

Deregulated expression of cytoskeleton related genes in the spinal cord and sciatic nerve of presymptomatic SOD1G93A Amyotrophic Lateral Sclerosis mouse model

Early molecular events related to cytoskeleton are poorly described in Amyotrophic Lateral Sclerosis (ALS), especially in the Schwann cell (SC), which offers strong trophic support to motor neurons. DAVID tool identified cytoskeleton-related genes by employing the Cellular Component Ontology (CCO) i...

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Bibliographic Details
Main Authors: Jessica Ruivo Maximino, Gabriela Pintar de Oliveira, Chrystian Junqueira Alves, Gerson eChadi
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Sciatic Nerve
Spinal Cord
ALS
SOD1G93A
pre-symptomatic
Kif1b microarray
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00148/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00148/full

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