Guided chemotherapy based on patient-derived mini-xenograft models improves survival of gallbladder carcinoma patients

Guided chemotherapy based on patient-derived mini-xenograft models improves survival of gallbladder carcinoma patients

Abstract Background Gallbladder carcinoma is highly aggressive and resistant to chemotherapy, with no consistent strategy to guide first line chemotherapy. However, patient-derived xenograft (PDX) model has been increasingly used as an effective model for in preclinical study of chemosensitivity. Me...

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Bibliographic Details
Main Authors: Ming Zhan, Rui-meng Yang, Hui Wang, Min He, Wei Chen, Sun-wang Xu, Lin-hua Yang, Qiang Liu, Man-mei Long, Jian Wang
Format: Article
Language:English
Published: Wiley 2018-07-01
Series:Cancer Communications
Subjects:
Gallbladder cancer
Mini-PDX
Chemosensitivity
Overall survival
Personalized therapy
Online Access:http://link.springer.com/article/10.1186/s40880-018-0318-8

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http://link.springer.com/article/10.1186/s40880-018-0318-8

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