Fluoxetine exerts age-dependent effects on behavior and amygdala neuroplasticity in the rat.

The selective serotonin reuptake inhibitor (SSRI) Prozac® (fluoxetine) is the only registered antidepressant to treat depression in children and adolescents. Yet, while the safety of SSRIs has been well established in adults, serotonin exerts neurotrophic actions in the developing brain and thereby...

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Bibliographic Details
Main Authors: Judith R Homberg, Jocelien D A Olivier, Tom Blom, Tim Arentsen, Chantal van Brunschot, Pieter Schipper, Gerdien Korte-Bouws, Gilles van Luijtelaar, Liesbeth Reneman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3031607?pdf=render