Inhibiting actin depolymerization enhances osteoblast differentiation and bone formation in human stromal stem cells

Remodeling of the actin cytoskeleton through actin dynamics is involved in a number of biological processes, but its role in human stromal (skeletal) stem cells (hMSCs) differentiation is poorly understood. In the present study, we demonstrated that stabilizing actin filaments by inhibiting gene exp...

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Bibliographic Details
Main Authors: Li Chen, Kaikai Shi, Charles Edward Frary, Nicholas Ditzel, Huimin Hu, Weimin Qiu, Moustapha Kassem
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Stem Cell Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506115000823