Design of novel proliposome formulation for antioxidant peptide, glutathione with enhanced oral bioavailability and stability

To develop proliposome formulations to improve the oral bioavailability of l-glutathione (GSH), GSH-loaded proliposomes were prepared using the granule method. Mannitol was selected as an effective excipient to achieve the desired particle size, entrapment efficiency (EE), and solubility for oral de...

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Bibliographic Details
Main Authors: Jong Chan Byeon, Sang-Eun Lee, Tae-Hyeon Kim, Jung Bin Ahn, Dong-Hyun Kim, Jin-Seok Choi, Jeong-Sook Park
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Drug Delivery
Subjects:
Online Access:http://dx.doi.org/10.1080/10717544.2018.1551441