The focal adhesion: a regulated component of aortic stiffness.

Increased aortic stiffness is an acknowledged predictor and cause of cardiovascular disease. The sources and mechanisms of vascular stiffness are not well understood, although the extracellular matrix (ECM) has been assumed to be a major component. We tested here the hypothesis that the focal adhesi...

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Bibliographic Details
Main Authors: Robert J Saphirstein, Yuan Z Gao, Mikkel H Jensen, Cynthia M Gallant, Susanne Vetterkind, Jeffrey R Moore, Kathleen G Morgan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3633884?pdf=render