Differential response of the liver to bile acid treatment in a mouse model of Niemann-Pick disease type C [version 1; referees: 2 approved, 1 not approved]
Niemann-Pick disease type C (NPC) disease is a neurodegenerative lysosomal storage disease caused by mutations in the NPC1 or NPC2 genes. Liver disease is also a common feature of NPC that can present as cholestatic jaundice in the neonatal period. Liver enzymes can remain elevated above the normal...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wellcome
2017-08-01
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| Series: | Wellcome Open Research |
| Subjects: | |
| Online Access: | https://wellcomeopenresearch.org/articles/2-76/v1 |