The Cross-Links of Endoplasmic Reticulum Stress, Autophagy, and Neurodegeneration in Parkinson’s Disease

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, and it is characterized by the selective loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc), as well as the presence of intracellular inclusions with α-synuclein as the main component in surv...

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Bibliographic Details
Main Authors: Haigang Ren, Wanqing Zhai, Xiaojun Lu, Guanghui Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
UPR
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.691881/full